A fatal case of 5-FU toxicity despite dose adjustment in a patient with a partial DPD deficiency receiving the FLOT regimen

Eur J Cancer. 2024 Jul:205:114102. doi: 10.1016/j.ejca.2024.114102. Epub 2024 May 6.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Antimetabolites, Antineoplastic / administration & dosage
  • Antimetabolites, Antineoplastic / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Dihydropyrimidine Dehydrogenase Deficiency* / complications
  • Fatal Outcome
  • Fluorouracil* / administration & dosage
  • Fluorouracil* / adverse effects
  • Humans

Substances

  • Antimetabolites, Antineoplastic
  • Fluorouracil