Which Factors Are Associated With Comorbid Psychiatric Conditions in Patients Affected by Substance Use Disorders? The Impact of COVID-19 Pandemic on Dual-Diagnosis Subjects

J Dual Diagn. 2024 Jul-Sep;20(3):201-209. doi: 10.1080/15504263.2024.2346519. Epub 2024 May 10.

Abstract

Objective: To investigate demographic/cinical variables associated to dual diagnosis and the psychological reaction of dual-diagnosis patients to COVID-19 pandemic.

Methods: Information was collected at the Addiction Service of Monza, Italy. The Impact of Event Scale-Revised (IES-R), a self-report questionnaire measuring the subjective response to a traumatic event, was administered. Univariate analyses and binary logistic regression were performed. IES-R scores were compared between groups defined by qualitative variables through one-way analyses of variance (ANOVA).

Results: 118 outpatients were included, 48.3% with dual diagnosis. Alcohol use disorder and being female were associated to dual diagnosis. IES-R scores were significantly higher in the dual-diagnosis group, especially for personality disorders (PDs). IES-R scores were higher in patients taking treatment for substance use disorder (SUD).

Conclusions: Females and alcohol abusers were at-risk subjects for dual diagnosis. Patients with SUD and PDs may benefit from additional support, especially when traumatic life events occur.

Trial registration: ClinicalTrials.gov Identifier: NCT04694482.

Keywords: COVID-19; Post Traumatic Stress Disorder (PTSD); Substance Use Disorder (SUD); dual diagnosis clinical factors; psychiatric comorbidity.

MeSH terms

  • Adult
  • COVID-19* / epidemiology
  • COVID-19* / psychology
  • Comorbidity*
  • Diagnosis, Dual (Psychiatry)
  • Female
  • Humans
  • Italy / epidemiology
  • Male
  • Mental Disorders / epidemiology
  • Middle Aged
  • Personality Disorders / diagnosis
  • Personality Disorders / epidemiology
  • Sex Factors
  • Substance-Related Disorders* / epidemiology

Associated data

  • ClinicalTrials.gov/NCT04694482