Puerarin inhibits the progression of hepatic carcinoma by suppressing NLRP3 inflammasome-mediated pyroptosis

Asian J Surg. 2024 Sep;47(9):4102-4103. doi: 10.1016/j.asjsur.2024.05.046. Epub 2024 May 13.

Authors

Yixiang Hu¹, Chao Hu², Haibo Lei¹, Xiang Liu³

Affiliations

¹ Molecular Pharmacology Laboratory, Department of Clinical Pharmacy, Xiangtan Center Hospital, Xiangtan, 411100, China.
² General Surgery Department, Xiangtan Center Hospital, Xiangtan, 411100, China.
³ Department of Clinical Pharmacy, Xiangtan Center Hospital, No. 120, Road Heping, Distract Yuhu, Xiangtan, 411100, China. Electronic address: [email protected].

PMID: 38744653
DOI: 10.1016/j.asjsur.2024.05.046

No abstract available

Publication types

Letter

MeSH terms

Animals
Carcinoma, Hepatocellular* / drug therapy
Carcinoma, Hepatocellular* / metabolism
Carcinoma, Hepatocellular* / pathology
Disease Progression*
Humans
Inflammasomes* / drug effects
Inflammasomes* / metabolism
Isoflavones* / pharmacology
Isoflavones* / therapeutic use
Liver Neoplasms* / drug therapy
Liver Neoplasms* / metabolism
Liver Neoplasms* / pathology
NLR Family, Pyrin Domain-Containing 3 Protein* / metabolism
Pyroptosis* / drug effects

Substances

NLR Family, Pyrin Domain-Containing 3 Protein
Inflammasomes
Isoflavones
puerarin
NLRP3 protein, human