Background: Ablation failures are common in case of intramural location of the arrhythmogenic substrate.
Case summary: We report the case of a patient with cardiomyopathy contributed by frequent monomorphic ventricular arrhythmias (VAs) from intramural basal interventricular septum treated with double-balloon venous ethanol ablation (VEA) after a previous failed endocardial radiofrequency (RF) ablation.
Discussion: Double-balloon VEA represents a safe and effective therapeutic option in case of intramural VAs also in the absence of venous collaterals joining selectively an intramural arrhythmic substrate.
Keywords: Alcoholization; Case Report; Catheter ablation; Premature ventricular complexes; Venous ethanol ablation; Ventricular tachycardia.
© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.