Abstract
A novel NIR fluorescent probe based on quinoline-conjugated benzo[cd]indol dual-salt for NADH was developed. This probe swiftly detects and responds sensitively to both endogenous and exogenous NADH alterations, enabling imaging of NADH fluctuations in type II diabetic and AD model cells.
MeSH terms
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Animals
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Diabetes Mellitus, Type 2
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Fluorescent Dyes* / chemical synthesis
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Fluorescent Dyes* / chemistry
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Humans
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Infrared Rays
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Mitochondria* / chemistry
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Mitochondria* / metabolism
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NAD* / analysis
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NAD* / chemistry
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Optical Imaging
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Quinolines / chemistry
Substances
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Fluorescent Dyes
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NAD
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Quinolines