An eosinophil peroxidase activity assay predicts acute exacerbations in post-operative chronic rhinosinusitis

Int Forum Allergy Rhinol. 2024 Sep;14(9):1517-1520. doi: 10.1002/alr.23366. Epub 2024 May 20.

Abstract

EPX activity has been correlated with eCRS diagnosis and baseline disease severity. Herein, EPX activity is shown to correlate with post-operative antibiotic and steroid use in CRS. EPX activity has potential to act as a prognostic biomarker of CRS disease severity and control.

Keywords: chronic rhinosinusitis; endoscopic sinus surgery; eosinophil peroxidase.

MeSH terms

  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Biomarkers / blood
  • Biomarkers / metabolism
  • Chronic Disease
  • Disease Progression
  • Eosinophil Peroxidase* / metabolism
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / diagnosis
  • Prognosis
  • Rhinitis* / diagnosis
  • Rhinosinusitis
  • Severity of Illness Index
  • Sinusitis* / diagnosis
  • Sinusitis* / surgery

Substances

  • Eosinophil Peroxidase
  • Biomarkers
  • Anti-Bacterial Agents