As our knowledge of the harmful effects of ultraviolet radiation continues to evolve, sunscreen remains an integral part of a comprehensive photoprotection strategy against multiple endpoints of ultraviolet-mediated damage. Part 1 of this review covers sunscreen active and additive ingredient properties, mechanisms of action and gaps in coverage. Following an overview of sunscreen's efficacy in protecting against sunburn, photocarcinogenesis, photoaging, pigmentary disorders, and idiopathic photodermatoses, we highlight considerations for product use and selection in children and individuals with skin of color.
Keywords: actinic keratoses; antioxidants; basal cell carcinoma; chemical filters; encapsulation; inorganic filters; iron oxide; keratinocyte carcinoma; melanoma; melasma; nanoparticles; organic filters; photoaging; photodermatoses; photoprotection; physical filters; pigmentation; squamous cell carcinoma; sunburn; sunscreen; tinted sunscreen; ultraviolet light; visible light.
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