Effects of Intravenous Lidocaine on Quality of Recovery After Laparoscopic Bariatric Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Obes Surg. 2024 Jul;34(7):2663-2669. doi: 10.1007/s11695-024-07300-7. Epub 2024 May 23.

Abstract

This systematic review and meta-analysis aimed to assess the effects of pre and intraoperative lidocaine infusion on short-term recovery quality after laparoscopic bariatric surgeries. In the search across MEDLINE, Embase, and Cochrane databases, we considered randomized controlled trials comparing intravenous lidocaine vs placebo (saline) for patients with obesity undergoing laparoscopic bariatric surgery. Seven studies (640 patients) were included. The lidocaine group had a significantly higher recovery quality score, a lower morphine consumption, and a notably reduced rate of nausea and vomiting compared with the placebo group. Additionally, Lidocaine infusion was associated with a shorter hospital stay, while no significant difference was observed in the time to bowel function recovery between both groups. In conclusion, lidocaine infusion before and during laparoscopic bariatric surgery contributes to an enhanced quality of recovery.

Keywords: Intravenous lidocaine; Laparoscopic bariatric surgery; Patients with obesity; Postoperative recovery.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Anesthetics, Local* / administration & dosage
  • Anesthetics, Local* / therapeutic use
  • Bariatric Surgery*
  • Humans
  • Infusions, Intravenous
  • Laparoscopy*
  • Length of Stay* / statistics & numerical data
  • Lidocaine* / administration & dosage
  • Lidocaine* / therapeutic use
  • Obesity, Morbid / surgery
  • Pain, Postoperative / drug therapy
  • Postoperative Nausea and Vomiting / prevention & control
  • Randomized Controlled Trials as Topic*
  • Recovery of Function / drug effects
  • Treatment Outcome

Substances

  • Anesthetics, Local
  • Lidocaine