A Network Approach to Understanding the Role of Executive Functioning and Alpha Oscillations in Inattention and Hyperactivity-Impulsivity Symptoms of ADHD

J Atten Disord. 2024 Aug;28(10):1357-1367. doi: 10.1177/10870547241253999. Epub 2024 May 26.

Abstract

Objective: ADHD is a prevalent neurodevelopmental disorder characterized by symptoms of inattention and hyperactivity-impulsivity. Impairments in executive functioning (EF) are central to models of ADHD, while alpha-band spectral power event-related decreases (ERD) have emerged as a putative electroencephalography (EEG) biomarker of EF in ADHD. Little is known about the roles of EF and alpha ERD and their interactions with symptoms of ADHD.

Method: We estimated network models of ADHD symptoms and integrated alpha ERD measures into the symptom network.

Results: EF emerges as a bridge network node connecting alpha ERD and the hyperactivity/impulsivity and inattention symptoms. We found that EF most closely relates to a subset of symptoms, namely the motoric symptoms, "seat" (difficulty staying seated), and "runs" (running or climbing excessively).

Conclusions: EF functions as a bridge node connecting alpha ERD and the ADHD symptom network. Motoric-type symptoms and EF deficits may constitute important nodes in the interplay between behavior/symptoms, cognition, and neurophysiological markers of ADHD.

Keywords: ADHD; EEG; IDA; alpha oscillations; executive functioning; network analysis.

MeSH terms

  • Adolescent
  • Alpha Rhythm* / physiology
  • Attention / physiology
  • Attention Deficit Disorder with Hyperactivity* / diagnosis
  • Attention Deficit Disorder with Hyperactivity* / physiopathology
  • Attention Deficit Disorder with Hyperactivity* / psychology
  • Brain / physiopathology
  • Child
  • Electroencephalography*
  • Executive Function* / physiology
  • Female
  • Humans
  • Impulsive Behavior* / physiology
  • Male