Multimodal imaging findings of primary liver clear cell carcinoma: a case presentation

Front Med (Lausanne). 2024 May 16:11:1408967. doi: 10.3389/fmed.2024.1408967. eCollection 2024.

Abstract

Primary clear cell carcinoma of liver (PCCCL) is a special and relatively rare subtype of hepatocellular carcinoma (HCC), which is more common in people over 50 years of age, with a preference for men and a history of hepatitis B or C and/or cirrhosis. Herein, we present a case of a 60-year-old woman who came to our hospital for medical help with right upper abdominal pain. The imaging examination showed a low-density mass in the right lobe of his liver. In contrast enhanced computed tomography (CT) or T1-weighted imaging, significant enhancement can appear around the tumor during the arterial phase, and over time, the degree of enhancement of the tumor gradually decreases. The lession showed obviously increased fluorine-18 fluorodeoxyglucose (18F-FDG) uptake on positron emission tomography/CT. These imaging findings contribute to the diagnosis of PCCCL and differentiate it from other types of liver tumors.

Keywords: MRI; PET/CT; clear cell carcinoma; imaging findings; liver.

Publication types

  • Case Reports

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This study was funded by the Guizhou Province Science and Technology Plan Project (grant numbers: Qiankehe-ZK [2024]-329) and Zunyi Science and Technology Joint Fund (Grant Number: HZ-2023-284).