Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report

Childs Nerv Syst. 2024 Sep;40(9):2957-2960. doi: 10.1007/s00381-024-06471-z. Epub 2024 May 31.

Abstract

Teratomas account for 18-20% of all intracranial germ cell tumors and mostly occur in the pineal region with only a few cases of pediatric sellar and suprasellar teratomas described in the literature. Here, we present a case of a child with an intracranial mature teratoma with pancreatic features causing vasospasm and subsequent stroke, found to be positive for CDKN2A-an independent variant associated with malignancy and small vessel disease leading to stroke.

Keywords: Intracranial teratoma; Paraneoplastic syndrome; Vasospasm.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms* / complications
  • Brain Neoplasms* / diagnostic imaging
  • Child
  • Female
  • Humans
  • Male
  • Paraneoplastic Syndromes
  • Stroke* / complications
  • Stroke* / diagnostic imaging
  • Stroke* / etiology
  • Teratoma* / complications
  • Teratoma* / diagnostic imaging
  • Teratoma* / surgery
  • Vasospasm, Intracranial* / diagnostic imaging
  • Vasospasm, Intracranial* / etiology