TriClip G4: A game-changer for tricuspid valve regurgitation treatment

Curr Probl Cardiol. 2024 Aug;49(8):102687. doi: 10.1016/j.cpcardiol.2024.102687. Epub 2024 May 29.

Abstract

Tricuspid valve regurgitation, or TR, is a difficult-to-manage condition. In addition to EVOQUE, percutaneous annuloplasty, and surgical repair, the TriClip G4 system has been added to the interventional therapeutic choices for TR. Recently, the Food and Drug Administration (FDA) approved the use of the TriClip G4 device to treat patients with symptomatic, severe TR who have received optimal medication therapy but are at intermediate or higher risk of surgery. This review attempts to offer a thorough examination of the procedural features, learning curves, results of the device and compares the TriClip G4 system to other interventional therapies for TR. TriClip G4 has shown to have promising results in pivotal clinical trials, be cost-effective, and improve the quality of life of patients. Furthermore, it has its unique advantages against other conventional techniques and devices.

Keywords: Clinical data; EVOQUE; Transcatheter edge-to-edge repair; TriClip G4; Tricuspid valve regurgitation.

Publication types

  • Review

MeSH terms

  • Cardiac Catheterization / methods
  • Cardiac Valve Annuloplasty / methods
  • Heart Valve Prosthesis
  • Heart Valve Prosthesis Implantation / instrumentation
  • Heart Valve Prosthesis Implantation / methods
  • Humans
  • Prosthesis Design
  • Treatment Outcome
  • Tricuspid Valve Insufficiency* / diagnosis
  • Tricuspid Valve Insufficiency* / surgery
  • Tricuspid Valve* / surgery