Effect of betulin oil on hair growth in hypothyroidism- a long-term blinded pilot study

Arch Dermatol Res. 2024 Jun 1;316(6):318. doi: 10.1007/s00403-024-02913-5.

Abstract

Background: One common problem in various patient groups is excessive hair loss on the head. One such group is people struggling with hypothyroidism. The market for preparations for hair growth and hair loss prevention includes betulin.

Purpose: This pilot study investigated its effect on hair loss in hypothyroid patients.

Study design: The study included a group of hypothyroid patients and a control group of people without hypothyroidism. Participants were randomly divided into a group taking placebo and betulin.

Methods: Results were investigated using photographic assessment of hair, trichoscopy and subjective evaluation of participants.

Conclusion: The study did not conclusively prove that betulin would contribute to the inhibition of hair loss or regrowth.

Keywords: Betula; Betulin; Hair loss; Hypothyroidism; Pilot study.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Alopecia / drug therapy
  • Betulinic Acid
  • Female
  • Hair* / drug effects
  • Hair* / growth & development
  • Humans
  • Hypothyroidism* / drug therapy
  • Male
  • Middle Aged
  • Pilot Projects
  • Plant Oils / administration & dosage
  • Treatment Outcome
  • Triterpenes* / administration & dosage
  • Triterpenes* / pharmacology

Substances

  • betulin
  • Triterpenes
  • Plant Oils
  • Betulinic Acid