Natural mycobacterium tuberculosis complex infection in a brown howler monkey (Alouatta guariba clamitans) in Brazil

J Med Primatol. 2024 Jun;53(3):e12716. doi: 10.1111/jmp.12716.

Abstract

Neotropical primates rarely exhibit active tuberculosis. A brown howler monkey was found injured in an urban area. Histopathology revealed granulomatous inflammation in the lungs, lymph nodes, and liver. Immunohistochemistry and molecular analysis confirmed the presence of Mycobacterium tuberculosis complex. The findings highlight the importance of TB surveillance in nonhuman primates.

Keywords: howler monkey; mycobacterium; new world primates; tuberculosis; zooanthroponosis.

Publication types

  • Case Reports

MeSH terms

  • Alouatta*
  • Animals
  • Brazil
  • Female
  • Male
  • Monkey Diseases* / microbiology
  • Monkey Diseases* / pathology
  • Mycobacterium tuberculosis* / isolation & purification
  • Tuberculosis* / microbiology
  • Tuberculosis* / pathology
  • Tuberculosis* / veterinary

Supplementary concepts

  • Alouatta guariba guariba