Concomitant ALK translocation and EGFR C797S mutation as resistance mechanisms to osimertinib in an EGFR-mutant NSCLC patient

Affiliations

• ¹ Nantes University, Centre Hospitalier Universitaire Nantes, Medical oncology, F-44000 Nantes, France; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, Nantes, France. Electronic address: [email protected].
• ² Nantes University, Centre Hospitalier Universitaire Nantes, Medical oncology, F-44000 Nantes, France; Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, Nantes, France.
• ³ Nantes University, Centre Hospitalier Universitaire Nantes, Pathology department, F-44000 Nantes, France.
• ⁴ Nantes University, Centre Hospitalier Universitaire Nantes, Medical oncology, F-44000 Nantes, France.
• ⁵ Nantes University, Centre Hospitalier Universitaire Nantes, Department of Bichemistry, F-44000 Nantes, France.
• ⁶ Nantes Université, Inserm UMR 1307, CNRS UMR 6075, Université d'Angers, CRCI2NA, Nantes, France; Nantes University, Centre Hospitalier Universitaire Nantes, Department of Bichemistry, F-44000 Nantes, France.