Conversion to open surgery in obese patients undergoing minimally invasive distal pancreatectomy: results from a multicenter analysis

HPB (Oxford). 2024 Sep;26(9):1172-1179. doi: 10.1016/j.hpb.2024.05.016. Epub 2024 May 29.

Abstract

Background: Although minimally invasive distal pancreatectomy (MIDP) is considered a standard approach it still presents a non-negligible rate of conversion to open that is mainly related to some difficulty factors, as obesity. The aim of this study is to analyze the preoperative factors associated with conversion in obese patients with MIDP.

Methods: In this multicenter study, all obese patients who underwent MIDP at 18 international expert centers were included. The preoperative factors associated with conversion to open surgery were analyzed.

Results: Out of 436 patients, 91 (20.9%) underwent conversion to open, presenting higher blood loss, longer operative time and similar rate of major complications. Twenty (22%) patients received emergent conversion. At univariate analysis, the type of approach, radiological invasion of adjacent organs, preoperative enlarged lymphnodes and ASA ≥ III were significantly associated with conversion to open. At multivariate analysis, robotic approach showed a significantly lower conversion rate (14.6 % vs 27.3%, OR = 2.380, p = 0.001). ASA ≥ III (OR = 2.391, p = 0.002) and preoperative enlarged lymphnodes (OR = 3.836, p = 0.003) were also independently associated with conversion.

Conclusion: Conversion rate is significantly lower in patients undergoing robotic approach. Radiological enlarged lymphnodes and ASA ≥ III are also associated with conversion to open. Conversion is associated with poorer perioperative outcomes, especially in case of intraoperative hemorrhage.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Blood Loss, Surgical
  • Chi-Square Distribution
  • Conversion to Open Surgery*
  • Europe
  • Female
  • Humans
  • Laparoscopy / adverse effects
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Obesity* / complications
  • Obesity* / surgery
  • Odds Ratio
  • Operative Time
  • Pancreatectomy* / adverse effects
  • Pancreatectomy* / methods
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Risk Factors
  • Robotic Surgical Procedures* / adverse effects
  • Time Factors
  • Treatment Outcome