Fatty liver disease: time to target CCR5?

Expert Opin Ther Targets. 2024 May;28(5):335-339. doi: 10.1080/14728222.2024.2366880. Epub 2024 Jun 13.
No abstract available

Keywords: CCR2; CCR5; Chemokine; GLP-1 receptor agonist; MASH; MASLD; NAFLD; NASH; T-cells; cenicriviroc; liver fibrosis; macrophages; maraviroc.

Publication types

  • Editorial

MeSH terms

  • Animals
  • CCR5 Receptor Antagonists / pharmacology
  • Humans
  • Molecular Targeted Therapy
  • Non-alcoholic Fatty Liver Disease / drug therapy
  • Non-alcoholic Fatty Liver Disease / physiopathology
  • Receptors, CCR5* / genetics
  • Receptors, CCR5* / metabolism

Substances

  • Receptors, CCR5
  • CCR5 protein, human
  • CCR5 Receptor Antagonists