Insulin Autoimmune Syndrome - An After-Meal Roller Coaster Ride

J ASEAN Fed Endocr Soc. 2024;39(1):125-128. doi: 10.15605/jafes.039.01.07. Epub 2024 Jan 7.

Abstract

Hypoglycemic disorders are rare in persons without diabetes, and clinical evaluation to identify its etiology can be challenging. We present a case of insulin autoimmune syndrome induced by carbimazole in a middle-aged Chinese man with underlying Graves' disease, which was managed conservatively with a combination of dietary modification and alpha-glucosidase inhibitor.

Keywords: endogenous hyperinsulinism; hypoglycemia; insulin antibodies.

Publication types

  • Case Reports

MeSH terms

  • Antithyroid Agents / adverse effects
  • Antithyroid Agents / therapeutic use
  • Autoimmune Diseases* / chemically induced
  • Carbimazole / adverse effects
  • Carbimazole / therapeutic use
  • Glycoside Hydrolase Inhibitors / adverse effects
  • Glycoside Hydrolase Inhibitors / therapeutic use
  • Graves Disease / drug therapy
  • Graves Disease / immunology
  • Humans
  • Insulin Antibodies / blood
  • Insulin*
  • Male
  • Middle Aged
  • Syndrome

Substances

  • Antithyroid Agents
  • Carbimazole
  • Glycoside Hydrolase Inhibitors
  • Insulin
  • Insulin Antibodies

Grants and funding

Funding Source None