Biphasic Calcium Phosphate in the Extraction Socket Preservation: A Systematic Review

J Pharm Bioallied Sci. 2024 Apr;16(Suppl 2):S1007-S1011. doi: 10.4103/jpbs.jpbs_1003_23. Epub 2024 Apr 16.

Abstract

Introduction: Various studies have suggested use of socket grafting materials after dental extraction for socket preservation. However, there is no single material that has been accepted as standard for preserving the socket. The purpose of this systematic review was to analyze the evidence for the use of biphasic calcium phosphate for socket regeneration.

Materials and methods: The team conducted a systematic literature search in accordance with the protocol registered at PROSPERO. PubMed, OVID, and EMBASE databases were used in the search. The articles were then screened using RAYYAN open-source software for the synthesis of evidence.

Results: Of the 240 articles found in the search, two studies could be included in the review.

Conclusion: Biphasic calcium phosphate (60% hydroxyapatite, HA and 40% beta-tricalcium phosphate, β-TCP) has a significant effect in the socket preservation and quality of bone regeneration.

Keywords: Bone substitute; extraction; graft; regeneration; repair; restoration; socket.

Publication types

  • Review