Association of mildly elevated pulmonary vascular resistance with major cardiovascular events in pulmonary hypertension and chronic kidney disease: A retrospective cohort analysis

Pulm Circ. 2024 Jun 17;14(2):e12401. doi: 10.1002/pul2.12401. eCollection 2024 Apr.

Abstract

Pulmonary hypertension (PH) is associated with adverse outcomes in chronic kidney disease (CKD) patients. Our study suggests mildly elevated pulmonary vascular resistance ( > 2 to ≤ 3) is independently associated with major adverse cardiovascular events at 1-year follow-up. Early diagnosis of precapillary PH in CKD patients can potentially improve clinical outcomes.

Keywords: hypertensive vascular renal disease; pulmonary hypertension; renal hemodynamics.