Trends and Missing Links in (De)Hydration Research: A Narrative Review

Nutrients. 2024 May 30;16(11):1709. doi: 10.3390/nu16111709.

Abstract

Despite decades of literature on (de)hydration in healthy individuals, many unanswered questions remain. To outline research and policy priorities, it is fundamental to recognize the literature trends on (de)hydration and identify current research gaps, which herein we aimed to pinpoint. From a representative sample of 180 (de)hydration studies with 4350 individuals, we found that research is mainly limited to small-scale laboratory-based sample sizes, with high variability in demographics (sex, age, and level of competition); to non-ecological (highly simulated and controlled) conditions; and with a focus on recreationally active male adults (e.g., Tier 1, non-athletes). The laboratory-simulated environments are limiting factors underpinning the need to better translate scientific research into field studies. Although, consistently, dehydration is defined as the loss of 2% of body weight, the hydration status is estimated using a very heterogeneous range of parameters. Water is the most researched hydration fluid, followed by alcoholic beverages with added carbohydrates (CHO). The current research still overlooks beverages supplemented with proteins, amino acids (AA), and glycerol. Future research should invest more effort in "real-world" studies with larger and more heterogeneous cohorts, exploring the entire available spectrum of fluids while addressing hydration outcomes more harmoniously.

Keywords: athlete; dehydration; fluid intake; health; hydration; performance; research gaps; sports; sports drinks; water.

Publication types

  • Review

MeSH terms

  • Adult
  • Dehydration* / prevention & control
  • Drinking / physiology
  • Female
  • Humans
  • Male
  • Water-Electrolyte Balance

Grants and funding

The publication fees were supported by National Funds through FCT—Fundação para a Ciência e a Tecnologia, I.P., within CINTESIS, R&D Unit (reference UIDB/4255/2020). CIFI2D is financed by the Portuguese Foundation for Science and Technology, under the https://doi.org/10.54499/UIDB/05913/2020. Bruna Ribeiro was funded by 2023.04302.BD.