Retinoic acid--a review

Am J Clin Nutr. 1979 Dec;32(12):2522-31. doi: 10.1093/ajcn/32.12.2522.

Abstract

Retinoic acid (RA) is now considered anormal metabolite of vitamin A. It has been established that RA maintains health and supports growth in animals but differs from other forms of vitamin A in that RA does not function in visual or reproductive processes. RA and RA analogs also differ from other forms of vitamin A in: absorption, transport, metabolism, storage, turnover, biochemical functions, excretion, pharmacology, and toxicology.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Female
  • Intestinal Absorption
  • Models, Biological
  • Pregnancy
  • Reproduction / drug effects
  • Stereoisomerism
  • Structure-Activity Relationship
  • Teratogens
  • Tretinoin / analogs & derivatives
  • Tretinoin / pharmacology
  • Tretinoin / physiology*
  • Tretinoin / toxicity
  • Urinary Bladder Neoplasms / chemically induced
  • Vision, Ocular / drug effects
  • Vitamin A / metabolism*

Substances

  • Teratogens
  • Vitamin A
  • Tretinoin