A Case of Gallbladder Metastasis of Malignant Melanoma

Acta Med Okayama. 2024 Jun;78(3):291-294. doi: 10.18926/AMO/67205.

Abstract

In the clinical course of malignant melanoma, which can metastasize to multiple organs, gallbladder metastases are rarely detected. A 69-year-old man who underwent resection of a primary malignant melanoma was subsequently treated with nivolumab for lung metastases and achieved complete response. Seven years after surgery, multiple nodules were found in the gallbladder, and he underwent laparoscopic cholecystectomy. The postoperative diagnosis was metastases of malignant melanoma. He has been recurrence-free 8 months after surgery. If radical resection is possible, such surgery should be performed for gallbladder metastases found in patients with other controlled lesions of malignant melanoma.

Keywords: gallbladder metastasis; laparoscopic cholecystectomy; malignant melanoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cholecystectomy, Laparoscopic
  • Gallbladder Neoplasms* / drug therapy
  • Gallbladder Neoplasms* / pathology
  • Gallbladder Neoplasms* / secondary
  • Gallbladder Neoplasms* / surgery
  • Humans
  • Lung Neoplasms / pathology
  • Lung Neoplasms / secondary
  • Male
  • Melanoma* / drug therapy
  • Melanoma* / pathology
  • Melanoma* / secondary
  • Nivolumab / therapeutic use
  • Skin Neoplasms / pathology
  • Skin Neoplasms / secondary

Substances

  • Nivolumab