Effects of percutaneous endovascular angioplasty for severe stenosis or occlusion of subclavian artery

Sci Rep. 2024 Jun 21;14(1):14290. doi: 10.1038/s41598-024-65302-y.

Abstract

To investigate the effect and safety of percutaneous endovascular angioplasty (PEA) with optional stenting for the treatment of severe stenosis or occlusion of subclavian artery, patients with severe stenosis ≥ 70% or occlusion of subclavian artery treated with PEA were retrospectively enrolled. The clinical data were analyzed. A total of 222 patients were retrospectively enrolled, including 151 males (68.0%) and 71 females (32.0%) aged 48-86 (mean 63.9 ± 9.0) years. Forty-seven (21.2%) patients had comorbidities. Subclavian artery stenosis ≥ 70% was present in 201 (90.5%) patients and complete subclavian occlusion in 21 (9.5%) cases. Angioplasty was successfully performed in all (100%) patients. Balloon-expandable stents were used in 190 (85.6%) cases, and self-expandable stents in 20 (9.0%) cases. Only 12 (5.4%) cases were treated with balloon dilation only. Among 210 patients treated with stent angioplasty, 71 (33.8% or 71/210) cases underwent balloon pre-dilation, 139 (66.2% or 139/210) had direct deployment of balloon-expandable stents, and 2 (1.0% or 2/210) experienced balloon post-dilation. Distal embolization protection devices were used in 5 (2.3% or 5/222) cases. Periprocedural complications occurred in 3 (1.4%) patients, including aortic dissection in 2 (0.9%) cases and right middle cerebral artery embolism in 1 (0.5%). No hemorrhage occurred. Among 182 (82.0%) patients with 6-month follow-up, restenosis > 70% occurred in 1 (0.5%) patient, and among 68 (30.6%) patients with 12-month follow-up, restenosis > 70% took place in 11 (16.2%) patients. Percutaneous endovascular angioplasty can be safely and efficiently performed for the treatment of severe stenosis ≥ 70% or occlusion of subclavian artery.

Keywords: Balloon expansion; Occlusion; Percutaneous endovascular angioplasty; Severe subclavian artery stenosis ≥ 70%; Stent deployment.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Angioplasty / adverse effects
  • Angioplasty / methods
  • Angioplasty, Balloon / adverse effects
  • Angioplasty, Balloon / methods
  • Arterial Occlusive Diseases / surgery
  • Arterial Occlusive Diseases / therapy
  • Constriction, Pathologic / therapy
  • Endovascular Procedures / adverse effects
  • Endovascular Procedures / methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Stents* / adverse effects
  • Subclavian Artery* / surgery
  • Subclavian Steal Syndrome / surgery
  • Subclavian Steal Syndrome / therapy
  • Treatment Outcome