Chronic Spontaneous Urticaria: Etiology and Pathogenesis

Eric T Oliver; Sarbjit S Saini

doi:10.1016/j.iac.2024.03.002

Chronic Spontaneous Urticaria: Etiology and Pathogenesis

Immunol Allergy Clin North Am. 2024 Aug;44(3):421-438. doi: 10.1016/j.iac.2024.03.002. Epub 2024 May 18.

Authors

Eric T Oliver¹, Sarbjit S Saini²

Affiliations

¹ Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle/ Room 3A. 18A, Baltimore, MD 21224, USA.
² Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins Asthma and Allergy Center, 5501 Hopkins Bayview Circle, Room 2B. 71B, Baltimore, MD 21224, USA. Electronic address: [email protected].

PMID: 38937007
DOI: 10.1016/j.iac.2024.03.002

Abstract

Urticaria, also known as hives, is a common condition thought to affect up to 20% of individuals worldwide in their lifetime. This skin condition is characterized by the appearance of pruritic, erythematous papules or plaques with superficial swelling of the dermis. The major complaint is the symptom of pruritus. Angioedema, which involves a deeper swelling of dermal or mucosal tissues, may accompany urticaria. Urticaria can be classified by both time course of symptoms and the underlying etiology.

Keywords: Basophils; Chronic urticaria; Eosinophils; Mast cells.

Publication types

Review

MeSH terms

Chronic Urticaria* / diagnosis
Chronic Urticaria* / etiology
Humans
Pruritus / diagnosis
Pruritus / etiology
Urticaria / diagnosis
Urticaria / etiology

Grants and funding

K23 AI139394/AI/NIAID NIH HHS/United States