The rapidly progressing and fatal outcome of rhombencephalitis by listeriosis in a 61-year-old male

Ann Agric Environ Med. 2024 Jun 27;31(2):311-314. doi: 10.26444/aaem/178178. Epub 2024 Mar 4.

Abstract

Listeria monocytogenes is a Gram-positive facultative anaerobic bacterium that is ubiquitous in the environment and can cause severe infections in immunocompromised individuals, pregnant women, and newborns. Listeriosis can manifest as meningitis, encephalitis, or sepsis, and its diagnosis requires a high index of suspicion. The case is reported of a rare presentation of rhombencephalitis by listeriosis in a 61-year-old male who initially suffered from subacute gastric disturbances and fever. Neurological consultation showed abnormal functions of cranial nerves and meningeal signs were observed. MRI revealed a poorly demarcated focus of approximately 45 × 16 × 15mm, indicating possible inflammatory processes, necessitating a lumbar puncture. Assessment of the CSF indicated infection with the bacterium- Listeria Monocytogenes, with the final diagnosis of Listeriosis encephalitis. Despite antibiotic therapy of Ceftazidine and Ampicillin, the patient's condition deteriorated, followed by death.

Keywords: brainstem inflammation; foodborne illness; listeriosis; listeriosis encephalitis; neuroinfection; rhombencephalitis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Encephalitis* / diagnosis
  • Encephalitis* / drug therapy
  • Encephalitis* / microbiology
  • Fatal Outcome
  • Humans
  • Listeria monocytogenes* / isolation & purification
  • Listeriosis* / diagnosis
  • Listeriosis* / drug therapy
  • Listeriosis* / microbiology
  • Male
  • Middle Aged
  • Rhombencephalon / microbiology

Substances

  • Anti-Bacterial Agents