Long-term follow-up of corrective jaw surgery including distraction osteogenesis in 32 patients with juvenile idiopathic arthritis

Int J Oral Maxillofac Surg. 2025 Feb;54(2):149-156. doi: 10.1016/j.ijom.2024.06.001. Epub 2024 Jun 29.

Abstract

Dentofacial deformity following juvenile idiopathic arthritis (JIA) with temporomandibular joint (TMJ) involvement is associated with functional, aesthetic, and psychosocial impairment. Corrective surgical treatment includes combinations of orthognathic surgeries (OS). The aims of this study were to assess orofacial symptoms, functional and aesthetic status, and stability after OS including mandibular distraction osteogenesis (MDO). A prospective study was conducted of 32 patients with JIA of the TMJ and dentofacial deformities who underwent MDO as the only surgery or in combination with bilateral sagittal split osteotomy, Le Fort I, and/or genioplastybetween 2003 and 2018. Data from clinical examinations and cephalograms performed pre- and postoperative and at long-term (mean 4 years) were analysed. Patients experienced unchanged orofacial symptoms (all P > 0.05), short-term TMJ functional impairment (all P < 0.001), and long-term morphological improvements in SNB angle (P < 0.001), anterior facial height (P < 0.001), mandibular length (P = 0.049), overjet (P < 0.001 and P = 0.005), and posterior facial symmetry (P = 0.046). MDO as the only surgery or with secondary adjunctive OS improved dentofacial morphology in terms of mandibular advancement, anterior facial height, posterior facial symmetry, and incisal relationships without long-term deterioration in TMJ function or orofacial symptoms.

Keywords: Cephalometry; Dentofacial deformities; Distraction osteogenesis; Juvenile arthritis; Orthognathic surgery; Temporomandibular joint disorders.

MeSH terms

  • Adolescent
  • Arthritis, Juvenile* / complications
  • Arthritis, Juvenile* / surgery
  • Cephalometry
  • Child
  • Dentofacial Deformities / surgery
  • Female
  • Follow-Up Studies
  • Genioplasty / methods
  • Humans
  • Male
  • Orthognathic Surgical Procedures* / methods
  • Osteogenesis, Distraction* / methods
  • Osteotomy, Le Fort
  • Prospective Studies
  • Temporomandibular Joint Disorders* / surgery
  • Treatment Outcome