Severe breakthrough hemolysis during compassionate use of Pegcetacoplan in paroxysmal nocturnal hemoglobinuria: managing an emergency

Blood Transfus. 2024 Jul 3;22(4):360-362. doi: 10.2450/BloodTransfus.639.

Authors

Elisabetta Metafuni¹, Antonella Carbone², Luca Petriccione², Sabrina Giammarco¹, Maria A Limongiello¹, Silvia Bellesi¹, Patrizia Chiusolo^{1

3}, Simona Sica^{1

3}

Affiliations

¹ Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica e Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
² Day Hospital Ematologia Cassino, ASL Frosinone, Ospedale Santa Scolastica, Cassino, Italy.
³ Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy.

No abstract available

Publication types

Case Reports

MeSH terms

Adult
Antibodies, Monoclonal, Humanized / adverse effects
Antibodies, Monoclonal, Humanized / therapeutic use
Compassionate Use Trials
Female
Hemoglobinuria, Paroxysmal* / blood
Hemoglobinuria, Paroxysmal* / drug therapy
Hemoglobinuria, Paroxysmal* / therapy
Hemolysis* / drug effects
Humans
Male

Substances

Antibodies, Monoclonal, Humanized