Mavacamten in Right Ventricular Outflow Tract Obstruction

Jasmine K Malhi; Richard T Carrick; Chloe Duvall; Faisal Rahman; Matthew W Martinez; Jose Madrazo; Lili A Barouch

doi:10.1016/j.jaccas.2024.102397

Mavacamten in Right Ventricular Outflow Tract Obstruction

JACC Case Rep. 2024 Jun 6;29(14):102397. doi: 10.1016/j.jaccas.2024.102397. eCollection 2024 Jul 17.

Authors

Jasmine K Malhi¹, Richard T Carrick¹, Chloe Duvall¹, Faisal Rahman¹, Matthew W Martinez², Jose Madrazo¹, Lili A Barouch¹

Affiliations

¹ Johns Hopkins University School of Medicine, Department of Medicine, Division of Cardiology, Baltimore, Maryland, USA.
² Chanin T. Mast Center for Hypertrophic Cardiomyopathy, Atlantic Health System, Morristown Medical Center, Morristown, New Jersey, USA.

Abstract

Right ventricular outflow tract (RVOT) obstruction is a rare complication of ventricular hypertrophy in patients with hypertrophic cardiomyopathy (HCM). This study presents an unusual case of a patient with HCM with severe RVOT obstruction that was relieved successfully through the use of mavacamten.

Keywords: cardiomyopathy; echocardiography; ejection fraction; left ventricle; murmur; right ventricle; treatment.

Publication types

Case Reports