Abstract
Rat coronavirus readily propagated and induced marked cytopathic effect in a rat cell line, LBC cell culture, which provided a sensitive, practical assay system for viral infectivity and neutralizing antibody, and a satisfactory source of the virus.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cell Line
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Coronaviridae / growth & development
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Coronaviridae / physiology*
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Cytopathogenic Effect, Viral
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Female
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Fluorescent Antibody Technique
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Mammary Neoplasms, Experimental
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Neutralization Tests
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Rats
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Rats, Inbred Lew
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Virus Cultivation
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Virus Replication*