Juvenile Nasopharyngeal Angiofibroma: A Series of 96 Surgical Cases

Int Arch Otorhinolaryngol. 2024 Jun 4;28(3):e432-e439. doi: 10.1055/s-0043-1777293. eCollection 2024 Jul.

Abstract

Introduction Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascularized tumor that affects almost exclusively male adolescents. Surgery is the treatment of choice for JNA. Objectives The present study is a 42-year retrospective review of a series of JNA cases treated surgically without previous embolization. Methods The present is a retrospective, descriptive study based on medical records of 96 patients with JNA who underwent microscopic or endoscopic excision without previous embolization from 1978 to 2020 in a single institution. The patients were categorized according to the Andrews et al. stage, and data were collected on age, gender, tumor staging, surgical approach, affected side, and outcome. Results All patients were male, with an average age of 17 years. The predominant tumor stage consisted of type II, with 52.1%. A total of 33.3% of the patients were submitted to the microscopic technique and 66.7%, to the endonasal technique. The rate of intraoperative blood transfusion was of 17.7%. Conclusion The present study reinforces that resection of JNA in various stages is viable without previous artery embolization.

Keywords: angiofibroma; intranasal surgery; nasopharyngeal neoplasms; surgery.

Grants and funding

Funding The authors declare that they have received no financial support from agencies in the public, private or non-profit sectors to conduct the present research.