miR-181c modulates SMAD7 and Parkin in human cardiac fibroblasts: Validation in frail older adults with diabetes and HFpEF

MeSH terms

• Age Factors
• Aged
• Aged, 80 and over
• Cells, Cultured
• Female
• Fibroblasts* / metabolism
• Fibroblasts* / pathology
• Frail Elderly
• Frailty / genetics
• Frailty / metabolism
• Heart Failure* / genetics
• Heart Failure* / metabolism
• Heart Failure* / pathology
• Heart Failure* / physiopathology
• Humans
• Male
• MicroRNAs* / genetics
• MicroRNAs* / metabolism
• Signal Transduction
• Stroke Volume
• Ubiquitin-Protein Ligases* / genetics
• Ubiquitin-Protein Ligases* / metabolism
• Ventricular Function, Left