Bilateral Lacrimal Gland Lymphoma - Case Presentation

Rom J Ophthalmol. 2024 Apr-Jun;68(2):191-197. doi: 10.22336/rjo.2024.36.

Abstract

Lacrimal gland lymphomas are rare orbital tumors, constituting a minor fraction of all orbital and ocular adnexal malignancies. This case study presents an 83-year-old male with bilateral lacrimal gland tumors, more prominent in the left orbit, causing decreased visual acuity, red eye, excessive tearing, and diplopia. Initial ophthalmological evaluations and imaging suggested bilateral lacrimal gland lymphoma, confirmed by histopathology as diffuse large B-cell non-Hodgkin lymphoma of the MALT type. Due to the significant tumor size and risk of visual function loss, surgical intervention was performed, followed by corticosteroid therapy. Postoperatively, a marked improvement in symptoms and a reduction in tumor size were observed. This case underscores the importance of comprehensive diagnostic approaches, including clinical, imaging, and histopathological evaluations, highlighting the need for a multidisciplinary approach in managing rare orbital tumors like lacrimal gland lymphoma. The patient's postoperative and follow-up care included oncological management to monitor and ensure long-term disease control and patient well-being. Abbreviations: RE = right eye, LE = left eye, CT = Computer tomography, MRI = Magnetic Resonance Imaging, TOD = intraocular pressure of right eye, TOS = intraocular pressure of left eye, US = ultrasound.

Keywords: B-cell lymphoma; MALT; lacrimal gland lymphomas; orbital tumors.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Biopsy
  • Eye Neoplasms / diagnosis
  • Eye Neoplasms / surgery
  • Eye Neoplasms / therapy
  • Humans
  • Lacrimal Apparatus / diagnostic imaging
  • Lacrimal Apparatus / pathology
  • Lacrimal Apparatus / surgery
  • Lacrimal Apparatus Diseases* / diagnosis
  • Lacrimal Apparatus Diseases* / surgery
  • Lymphoma, B-Cell, Marginal Zone / diagnosis
  • Lymphoma, B-Cell, Marginal Zone / surgery
  • Lymphoma, Large B-Cell, Diffuse / diagnosis
  • Lymphoma, Large B-Cell, Diffuse / surgery
  • Magnetic Resonance Imaging*
  • Male
  • Ophthalmologic Surgical Procedures / methods
  • Tomography, X-Ray Computed*
  • Visual Acuity