CD3+TCRαβ/CD19+-depleted stem cell boost and CD45RO+ memory T-cell add-back as a successful salvage treatment for poor graft function unresponsive to eltrombopag, following a second allogenic HSCT

Pediatr Blood Cancer. 2024 Oct;71(10):e31203. doi: 10.1002/pbc.31203. Epub 2024 Jul 15.
No abstract available

Publication types

  • Letter
  • Case Reports

MeSH terms

  • Antigens, CD19 / immunology
  • Benzoates* / therapeutic use
  • CD3 Complex
  • Child
  • Female
  • Hematopoietic Stem Cell Transplantation* / methods
  • Humans
  • Hydrazines* / therapeutic use
  • Leukocyte Common Antigens
  • Lymphocyte Depletion
  • Male
  • Memory T Cells / immunology
  • Pyrazoles* / therapeutic use
  • Receptors, Antigen, T-Cell, alpha-beta
  • Salvage Therapy* / methods
  • Transplantation, Homologous

Substances

  • eltrombopag
  • Hydrazines
  • Benzoates
  • Pyrazoles
  • Antigens, CD19
  • Receptors, Antigen, T-Cell, alpha-beta
  • CD3 Complex
  • Leukocyte Common Antigens
  • CD19 molecule, human