Altered circadian gene expression in primary human airway epithelial cells in asthma

Weston T Powell; Lindsay V Clark; Lucille M Rich; Elizabeth R Vanderwall; Camille Gates; Maria P White; Jason S Debley

doi:10.1183/23120541.00005-2024

Altered circadian gene expression in primary human airway epithelial cells in asthma

ERJ Open Res. 2024 Jul 15;10(4):00005-2024. doi: 10.1183/23120541.00005-2024. eCollection 2024 Jul.

Authors

Weston T Powell¹, Lindsay V Clark¹, Lucille M Rich¹, Elizabeth R Vanderwall¹, Camille Gates¹, Maria P White¹, Jason S Debley¹

Affiliation

¹ Center for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle Children's Hospital, Department of Pediatrics, Pulmonary and Sleep Medicine, University of Washington, Seattle, WA, USA.

Abstract

Primary human airway epithelial cells demonstrate altered rhythmic gene expression in cytokine-related pathways in asthma with intact core circadian gene expression https://bit.ly/3v9lOC6.

Associated data

Dryad/10.5061/dryad.1jwstqk2g

Grants and funding

R01 AI163160/AI/NIAID NIH HHS/United States