Outcomes and Attributes Patients Value When Choosing Glucose-Lowering Medications: A Mixed-Methods Study

Elizabeth H Golembiewski; Andrea E Garcia Bautista; Eric Polley; Guillermo E Umpierrez; Rodolfo J Galindo; Juan P Brito; Victor M Montori; Janet P Gockerman; Michael Tesulov; Bertina Labatte; Mindy M Mickelson; Rozalina G McCoy

doi:10.2337/cd23-0042

Outcomes and Attributes Patients Value When Choosing Glucose-Lowering Medications: A Mixed-Methods Study

Clin Diabetes. 2024 Summer;42(3):371-387. doi: 10.2337/cd23-0042. Epub 2024 Jan 22.

Authors

Affiliations

¹ Knowledge and Evaluation Research (KER) Unit, Mayo Clinic, Rochester, MN.
² Department of Public Health Sciences, University of Chicago, Chicago, IL.
³ Division of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, GA.
⁴ Division of Endocrinology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL.
⁵ Division of Endocrinology, Department of Medicine, Mayo Clinic, Rochester, MN.
⁶ Patient investigator, Grand Rapids, MI.
⁷ Patient investigator, Rochester, MN.
⁸ Division of Endocrinology, Diabetes, & Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.
⁹ University of Maryland Institute for Health Computing, Bethesda, MD.

PMID: 39015157
PMCID: PMC11247043 (available on 2025-06-01)
DOI: 10.2337/cd23-0042

Abstract

This mixed-methods study sought to identify pharmacotherapy preferences among 40 noninsulin-treated adults with type 2 diabetes receiving care at two U.S. health care systems. Participants ranked by relative importance various health outcomes and medication attributes and then contextualized their rankings. Most participants ranked blindness (63%), death (60%), heart attack (48%), and heart failure (48%) as the most important health outcomes and glucose-lowering efficacy (68%) as the most important medication attribute, followed by oral administration (45%) and lack of gastrointestinal side effects (38%).

Associated data

figshare/10.2337/figshare.24932730

Grants and funding

Research reported in this publication was funded through a Patient-Centered Outcomes Research Institute (PCORI) award (DB-2020C2-20306). The statements in this publication are solely the responsibility of the authors and do not necessarily represent the views of PCORI, its Board of Governors, or its Methodology Committee.