Comparative study of 155Tb production via 155Dy precursor with p, d and α beams on natural targets for medical applications

Appl Radiat Isot. 2024 Oct:212:111443. doi: 10.1016/j.apradiso.2024.111443. Epub 2024 Jul 14.

Abstract

Three different reactions with the use of natural targets are investigated to produce 155Tb for medical applications from the decay of its precursor 155Dy. The TALYS code has been exploited to optimize the cross section description and to improve the agreement with the full set of available data. The study is completed by a theoretical model for the two radio-chemical separations: optimal solutions are presented for the production of high quality 155Tb samples, guaranteed by the absence of the main contaminant, 156Tb.

Keywords: Deuteron and α induced nuclear reactions; Medical radionuclide indirect production; Nuclear reaction modeling; Proton.

Publication types

  • Comparative Study

MeSH terms

  • Alpha Particles / therapeutic use
  • Phosphorus
  • Terbium* / chemistry

Substances

  • Terbium
  • Phosphorus