Healthcare professionals' perspectives towards the digitalisation of paediatric growth hormone therapies: expert panels in Italy and Korea

Front Endocrinol (Lausanne). 2024 Jul 10:15:1419667. doi: 10.3389/fendo.2024.1419667. eCollection 2024.

Abstract

Introduction: To analyse the perspectives of healthcare professionals (HCPs) regarding the acceptance of digital health solutions for growth hormone (GH) deficiency care. This study identified factors impacting HCPs' intent to use and recommend digital solutions supporting recombinant-human growth hormone (r-hGH) therapy in Italy and Korea with a use case of connected drug delivery system (Aluetta® with Smartdot™) integrated in a platform for GH treatment support (the Growzen™ digital health ecosystem).

Methods: Participatory workshops were conducted in Rome, Italy, and Seoul, Korea, to collect the perspectives of 22 HCPs on various predefined topics. HCPs were divided into two teams, each moderated by a facilitator. The workshops progressed in five phases: introduction of the project and experts, capturing views on the current context of digitalisation, perceived usefulness and ease of use of Aluetta® with Smartdot™, exploration of the perception of health technology evolution, and combined team recommendations. Data shared by HCPs on technology acceptance were independently analysed using thematic analysis, and relevant findings were shared and validated with experts.

Results: HCPs from both Italy and Korea perceived Aluetta® with Smartdot™ and the Growzen™ based digital health ecosystem as user-friendly, intuitive, and easy-to-use solutions. These solutions can result in increased adherence, a cost-effective healthcare system, and medication self-management. Although technology adoption and readiness may vary across countries, it was agreed that using digital solutions tailored to the needs of users may help in data-driven clinical decisions and strengthen HCP-patient relationships.

Conclusion: HCPs' perspectives on the digitalisation in paediatric GH therapies suggested that digital solutions enable automatic, real-time injection data transmission to support adherence monitoring and evidence-based therapy, strengthen HCP-patient relationships, and empower patients throughout the GH treatment process.

Keywords: Aluetta®Smartdot™; adherence monitoring; connected device; digital health; healthcare digitalisation; recombinant human growth hormone.

MeSH terms

  • Attitude of Health Personnel
  • Child
  • Drug Delivery Systems / methods
  • Female
  • Growth Disorders / drug therapy
  • Health Personnel* / psychology
  • Human Growth Hormone* / administration & dosage
  • Human Growth Hormone* / therapeutic use
  • Humans
  • Italy
  • Male
  • Republic of Korea
  • Telemedicine

Substances

  • Human Growth Hormone

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. The authors declare that this study received funding from Merck (CrossRef Funder ID: 10.13039/100009945). The funder was involved in the writing of this article and the decision to submit it for publication.