Quality of life in childhood immune thrombocytopenia: Revision of the Kids' ITP Tools (KIT)

Br J Haematol. 2024 Oct;205(4):1489-1496. doi: 10.1111/bjh.19662. Epub 2024 Jul 27.

Abstract

The Kids ITP Tools (KIT) is a health-related quality of life (HRQoL) questionnaire that evaluates quality of life in children with immune thrombocytopenia (ITP). There are three formats: Child Self-Report, Parent Proxy-Report and Parent Impact-Report. This study aimed to develop a domain structure by grouping-related questions from the questionnaire into domains that independently reflect various aspects of HRQoL. The study was conducted in two phases. Phase 1 involved an online survey distributed to experts to identify conceptual domains for the KIT. Phase 2 utilized a statistical approach to analyse responses from patients with ITP and their families. A revised KIT 2.0 was ultimately developed to aid in treatment decision-making and monitoring of ITP.

Keywords: immune thrombocytopenia; paediatric bleeding disorders; quality of life.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Parents / psychology
  • Purpura, Thrombocytopenic, Idiopathic* / therapy
  • Quality of Life*
  • Surveys and Questionnaires