Early Outcomes of Prostatic Artery Embolization using n-Butyl Cyanoacrylate Liquid Embolic Agent: A Safety and Feasibility Study

J Vasc Interv Radiol. 2024 Dec;35(12):1855-1861. doi: 10.1016/j.jvir.2024.07.018. Epub 2024 Jul 27.

Abstract

This retrospective study evaluated the feasibility, safety, and short-term effectiveness of prostatic artery embolization (PAE) using n-butyl cyanoacrylate (nBCA) glue embolization in 244 patients from June 2022 through May 2024. Technical success, defined as bilateral glue embolization, was achieved in 95% of cases. The median fluoroscopy time was 22.2 minutes (interquartile range [IQR], 17.1-30.0 minutes), and the median air kerma was 753 mGy (IQR, 417-1,559 mGy). Compared with baseline, statistically significant improvements were observed at 7.1 weeks for the International Prostate Symptom Score (9.5 [SD ± 6.0] vs 20.5 [SD ± 6.7]; P < .01), quality of life (1.8 [SD ± 1.5] vs 4.0 [SD ± 1.1]; P < .01), Qmax (10.4 mL/s [SD ± 6.3] vs 6.1 mL/s [SD ± 2.5]; P < .01), and prostate grand volume at 6 months (113.3 mL [SD ± 69.3] vs 156.6 mL [SD ± 104.6]; P < .01). These results demonstrate the use of nBCA for PAE as a technically feasible and safe option with excellent short-term outcomes.

MeSH terms

  • Aged
  • Embolization, Therapeutic* / adverse effects
  • Enbucrilate* / administration & dosage
  • Enbucrilate* / adverse effects
  • Feasibility Studies*
  • Humans
  • Lower Urinary Tract Symptoms / diagnostic imaging
  • Lower Urinary Tract Symptoms / etiology
  • Lower Urinary Tract Symptoms / physiopathology
  • Lower Urinary Tract Symptoms / therapy
  • Male
  • Middle Aged
  • Prostate* / blood supply
  • Prostatic Hyperplasia* / diagnostic imaging
  • Prostatic Hyperplasia* / therapy
  • Quality of Life
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome

Substances

  • Enbucrilate