High - but not standard-dose atorvastatin prevents the increase of plasma matrix metalloproteinase-2 triggered by acute coronary syndromes

Coron Artery Dis. 2024 Nov 1;35(7):622-624. doi: 10.1097/MCA.0000000000001414. Epub 2024 Sep 19.
No abstract available

MeSH terms

  • Acute Coronary Syndrome* / blood
  • Acute Coronary Syndrome* / drug therapy
  • Aged
  • Atorvastatin* / administration & dosage
  • Biomarkers / blood
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors* / administration & dosage
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors* / therapeutic use
  • Male
  • Matrix Metalloproteinase 2* / blood
  • Matrix Metalloproteinase 2* / metabolism
  • Middle Aged
  • Treatment Outcome

Substances

  • Atorvastatin
  • Matrix Metalloproteinase 2
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • MMP2 protein, human
  • Biomarkers