Ex vivo heart perfusion: an updated systematic review

Heart Fail Rev. 2024 Sep;29(5):1079-1096. doi: 10.1007/s10741-024-10420-y. Epub 2024 Aug 2.

Abstract

Due to the discrepancy between patients awaiting a heart transplant and the availability of donor hearts, strategies to expand the donor pool and improve the transplant's success are crucial. This review aims to summarize current knowledge on the ex vivo heart preservation (EVHP) experience as an alternative to standard cold static storage (CSS). EVHP techniques can improve the preservation of the donor's heart before transplantation and allow for pre-transplant organ evaluation.

Keywords: Ex vivo machine perfusion; Heart preservation; Heart transplantation.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Heart Transplantation* / methods
  • Humans
  • Organ Preservation* / methods
  • Perfusion* / methods
  • Tissue Donors