Genome sequences of human anelloviruses in the Lamedtorquevirus, Memtorquevirus, and Samektorquevirus genera identified from the female genital tract

Eric D Do; Steven C Holland; Emily A Kaelin; Caroline Mitchell; Jaime Soria; Alberto La Rosa; Eduardo Ticona; Robert W Coombs; Lisa M Frenkel; Marta E Bull; Efrem S Lim

doi:10.1128/mra.00582-24

Genome sequences of human anelloviruses in the Lamedtorquevirus, Memtorquevirus, and Samektorquevirus genera identified from the female genital tract

Microbiol Resour Announc. 2024 Sep 10;13(9):e0058224. doi: 10.1128/mra.00582-24. Epub 2024 Aug 5.

Authors

Eric D Do^#¹, Steven C Holland^#², Emily A Kaelin^{1

2}, Caroline Mitchell³, Jaime Soria⁴, Alberto La Rosa^{5

6}, Eduardo Ticona⁷, Robert W Coombs⁸, Lisa M Frenkel^{8

9

10}, Marta E Bull^{9

10}, Efrem S Lim^{1

2}

Affiliations

¹ School of Life Sciences, Arizona State University, Tempe, Arizona, USA.
² Center for Fundamental and Applied Microbiomics, the Biodesign Institute, Tempe, Arizona, USA.
³ Department of Obstretrics and Gynecology, University of Washington, Seattle, Washington, USA.
⁴ Infectious Diseases Departmento, Hospital Nacional Dos de Mayo, Universidad de San Marcos, Lima, Peru.
⁵ Asociaciòn Civil Impacta Salud y Educación, Lima, Peru.
⁶ MSD Peru, Lima, Peru.
⁷ Infectious Diseases Departamento, Hospital Nacional Dos de Mayo, Asociaciòn Civil Impacta Salud y Educación, Universidad de San Marcos, Lima, Peru.
⁸ Departments of Medicine; Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
⁹ Seattle Children's Research Institute, Seattle, Washington, USA.
¹⁰ Department of Pediatrics, University of Washington, Seattle, Washington, USA.

^# Contributed equally.

Abstract

We identified and characterized seven anellovirus genome sequences in the female genital tract through virome metagenomic sequencing of cervicovaginal lavage specimens from women living with HIV in Peru. Phylogenetic and genomic analyses indicate that they belong to three newly proposed Lamedtorquevirus, Memtorquevirus, and Samektorquevirus genera in the Anelloviridae family.

Keywords: Anelloviridae; female genital tract.

Abstract

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