Hyperaldosteronism and hyperparathyroidism. A disturbing friendship

Nefrologia (Engl Ed). 2024 Jul-Aug;44(4):496-502. doi: 10.1016/j.nefroe.2024.07.007. Epub 2024 Aug 5.

Abstract

Classically, aldosterone actions are associated with the stability of the effective circulating volume and with blood pressure control, while parathormone actions are linked to bone mineral metabolism, calcium, and phosphate homeostasis. Nevertheless, the relationship between these two hormonal axes surpasses these areas. A bidirectional interrelation between calcium-phosphorus metabolism and blood pressure control can lead to alterations in both. This can have significant implications for the evolution and treatment of patients. To illustrate this relationship, we present two clinical cases that demonstrate the pathophysiology involved.).

Keywords: Blood pressure; Calcium-sensing receptor; Hiperaldosteronismo; Hiperparatiroidismo; Hyperaldosteronism; Hyperparathyroidism; Receptor sensible de calcio; Tensión arterial.

Publication types

  • Case Reports

MeSH terms

  • Aldosterone / blood
  • Calcium / blood
  • Female
  • Humans
  • Hyperaldosteronism* / complications
  • Hyperaldosteronism* / etiology
  • Hyperparathyroidism / complications
  • Male
  • Middle Aged
  • Parathyroid Hormone / blood

Substances

  • Calcium
  • Parathyroid Hormone
  • Aldosterone