[Renal failure and drug-drug interactions]

MMW Fortschr Med. 2024 Aug;166(13):39-43. doi: 10.1007/s15006-024-4103-0.
[Article in German]

Abstract

Renal failure is common and comes with a steep increasing prevalence in older patients. It is a frequent aspect in multimorbidity and associated with polypharmacia. Based on available literature an overview is given concerning important drug-drug interactions and how to avoid or manage them. Among a large variety of possible interactions anticoagulation and diuretic therapy still represent the highest clinical relevance.

Keywords: Renal failure; drug-drug interaction.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Aged
  • Anticoagulants / adverse effects
  • Anticoagulants / therapeutic use
  • Diuretics / adverse effects
  • Diuretics / therapeutic use
  • Drug Interactions*
  • Humans
  • Polypharmacy
  • Renal Insufficiency* / chemically induced

Substances

  • Diuretics
  • Anticoagulants