Cutaneous side effects of treatment with immune checkpoint inhibitors

Ugeskr Laeger. 2024 Jul 15;186(29):V03240216. doi: 10.61409/V03240216.
[Article in Danish]

Abstract

Over the past decade, treatment with immune checkpoint inhibitors (ICI) has been implemented in cancer treatment. It has led to a significant improvement in the prognosis for many types of cancer. ICIs work by inducing the body's immune response against cancer cells. Unfortunately, they can also cause immune-related adverse events in most organ systems, with skin-related adverse events being among the most common. This review provides an overview of existing evidence and clinical experience regarding managing dermatological adverse events associated with ICIs.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Drug Eruptions* / etiology
  • Humans
  • Immune Checkpoint Inhibitors* / adverse effects
  • Neoplasms / drug therapy

Substances

  • Immune Checkpoint Inhibitors