During a viral infection, several membraneless compartments with liquid properties are formed. They can be of viral origin concentrating viral proteins and nucleic acids, and harboring essential stages of the viral cycle, or of cellular origin containing components involved in innate immunity. This is a paradigm shift in our understanding of viral replication and the interaction between viruses and innate cellular immunity.
Keywords: Condensate; Innate immunity; Liquid-liquid phase separation; Membraneless organelle; Viral factory; Viral replication.
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