Silicone oil (SO) is commonly used as a retinal tamponade during pars plana vitrectomy for complicated retinal detachments. Although fairly inert, complications such as cataract formation, intraocular pressure elevation, corneal changes, inner retinal thinning, and optic neuropathy have been noted. We report two cases of postoperative subfoveal outer retinal lucency and hyperreflective deposits following SO insertion and resolution following removal. [Ophthalmic Surg Lasers Imaging Retina 2024;55:675-678.].