Estrogen Receptor-targeted PET Imaging for Breast Cancer

Radiology. 2024 Aug;312(2):e240315. doi: 10.1148/radiol.240315.

Abstract

Two complementary patient cases are presented to highlight the importance of estrogen receptor (ER)-targeting imaging in treatment planning and selection for endocrine therapy in breast cancer patients. This article will discuss the radiopharmaceuticals and biology, imaging interpretation, and current clinical applications of ER-targeting imaging using fluorine 18 fluoroestradiol PET.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Breast Neoplasms* / diagnostic imaging
  • Breast Neoplasms* / metabolism
  • Estradiol
  • Female
  • Humans
  • Middle Aged
  • Positron-Emission Tomography* / methods
  • Radiopharmaceuticals* / pharmacokinetics
  • Receptors, Estrogen* / metabolism

Substances

  • Radiopharmaceuticals
  • Receptors, Estrogen
  • Estradiol