Nail involvement in Langerhans cell histiocytosis is rarely reported in the literature. According to the reported cases, it is believed that the involvement of nails has a poor prognosis because of multisystem involvement. Performing a nail bed biopsy might be challenging for children. We report a child in whom nail bed biopsy served as the sole clue to the diagnosis of Langerhans cell histiocytosis in absentia of skin clue on a background of advanced multisystem involvement.
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